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Thorne Methyl-Guard Plus

Product information reviewedManufacturer ThorneDocumentation Manufacturer catalog reviewed

$62.00

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Support cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation*

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SKU: SF789 Category: Tag:

Product overview

Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.*

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*

 

Benefits of Thorne Methyl-Guard Plus

  • Nutritional support for individuals who have MTHFR gene variations*
  • Enhanced cellular energy production fights occasional fatigue*
  • Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*
  • Promotes fat metabolism and lean body composition*
  • Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*
  • Promotes liver detoxification of many substances, including hormones like estrogen*

 

Why is methylation important?

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

  • Cardiovascular health
  • Cellular energy production
  • Fat metabolism
  • Neurological function
  • DNA production
  • Liver detoxification processes
  • Eye health
  • Histamine balance

 

Who can benefit from Thorne Methyl-Guard Plus

  • Individuals with variations to MTHFR and other genes that adversely affect methylation*
  • Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*
  • Women seeking support for estrogen metabolism and bone health*
  • Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*
  • Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

 

Features of Thorne Methyl-Guard Plus

  • Betaine, also known as trimethylglycine, is a superior methyl donor 
  • The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*
  • Active forms of vitamins B2 and B6 – key cofactors in methylation processes
  • B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*
  • Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

How to use

Take 1-3 capsules daily or as recommended by your health-care practitioner.

Ingredient information

Serving size3 Capsule(s)Package count90 capsules

Ingredient amounts

Betaine Anhydrous (Trimethylglycine)
1.8 g
Folate (L-5-MTHF)
5 mg DFE
Vitamin B12 (as Methylcobalamin)
3 mg
Vitamin B6 (as Pyridoxal 5'-Phosphate)
45 mg
Vitamin B2 (Riboflavin 5'-Phosphate Sodium)
90 mg
Other ingredients

Calcium (Citrate), Calcium Laurate, Hypromellose (derived from cellulose) capsule

Product details

Brand
Thorne
Form
Capsule
Package count
90 capsules
Manufacturer
Thorne

Related wellness areas

EnergyHeart & VesselsHormone SupportMen's HealthMethylation

Warnings

ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Manufacturer attributes

Thorne Verified

These product attributes are reported in Thorne’s current manufacturer catalog. Select an attribute to read Thorne’s definition.

View this product in Thorne’s catalog ↗

Shipping & delivery

We ship through UPS to the contiguous United States (48 states and Washington, DC).

Shipping options

  • UPS Ground — $15
  • UPS 3 Day Select — $25
  • UPS Next Day Air — $49

Order processing

  • We process orders Monday through Saturday.
  • Paid, confirmed orders received before 6:00 PM Eastern Time are generally prepared the same day, subject to carrier pickup availability.
  • Orders awaiting payment do not ship until payment is confirmed.

Shipping area

  • We do not ship to Alaska, Hawaii, Puerto Rico, or international destinations.
  • Transit time begins when UPS accepts the shipment.

Tracking

  • Tracking is emailed after the order ships.
  • Carrier delivery estimates are not guarantees.

Free UPS 2nd Day Air

  • A merchandise subtotal of $200 or more after discounts and before tax qualifies within our shipping area.
  • Shipping charges do not count toward the minimum. UPS 2nd Day Air is not offered as a paid option.

Shipping FAQ

When will my order ship?

Paid, confirmed orders received before 6:00 PM Eastern Time are generally prepared for same-day shipping Monday through Saturday, subject to carrier pickup availability. Orders after the cutoff, on Sundays, or on major holidays are processed on the next available shipping day.

Where does Cross Wellness ship?

We ship only to the contiguous United States: the 48 states and Washington, DC. Alaska, Hawaii, Puerto Rico, and international destinations are not currently eligible.

How do I track my order?

Tracking information is emailed after shipment. For delivery questions, contact shipping@crosswellness.com and include your order number.

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